Research and Therapeutic Approaches in Stem Cell Genome Editing by CRISPR Toolkit
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Optimization of IL-1RA structure to achieve a smaller protein with a higher affinity to its receptor.
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Principles and Applications of CRISPR Toolkit in Virus Manipulation, Diagnosis, and Virus-Host Interactions.
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Weighted correlation network analysis revealed novel long non-coding RNAs for colorectal cancer.
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Enhanced High Mutation Rate and Natural Selection to Produce Attenuated Viral Vaccine with CRISPR Toolkit in RNA Viruses especially SARS-CoV-2.
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Differences and similarities between mesenchymal stem cell and endothelial progenitor cell immunoregulatory properties against T cells.
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Post-decellularization techniques ameliorate cartilage decellularization process for tissue engineering applications.
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Single-cell transcriptomic profiling and characterization of endothelial progenitor cells: new approach for finding novel markers.
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Human fetal liver MSCs are more effective than adult bone marrow MSCs for their immunosuppressive, immunomodulatory, and Foxp3+ T reg induction capacity.
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TNFα priming through its interaction with TNFR2 enhances endothelial progenitor cell immunosuppressive effect: new hope for their widespread clinical application.
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Current Preventions and Treatments of aGVHD: From Pharmacological Prophylaxis to Innovative Therapies.
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TNFR2 Is a Crucial Hub Controlling Mesenchymal Stem Cell Biological and Functional Properties.
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Regulatory T cell induction by Mesenchymal stem cells depends on the expression of TNFR2 by T cells.
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TNFα-TNFR2 signaling pathway in control of the neural stem/progenitor cell immunosuppressive effect: Different experimental approaches to assess this hypothetical mechanism behind their immunological function.
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TNFα/TNFR2 signaling pathway: an active immune checkpoint for Mesenchymal stem cell immunoregulatory function.
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The TNF/TNFR2 signaling pathway is a key regulatory factor in endothelial progenitor cell immunosuppressive effect.
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Different approaches for transformation of Mesenchymal stem cells into hepatocyte-like cells.
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Chief Executive Officer (CEO)
Sina Naserian, Ph.D. is researcher at INSERM (National Institute for Medical Research) located at Paul Brousse Hospital (Villejuif, France). Performing a Biomedical Engineering master he has a good vision of medical devices and kits. With a Ph.D. degree in immunology, he is specialist of Immunological Tolerance and Alloimmunity. His research interest is in the field of Stem Cell and Immune Therapy. He is applied in many scientific and industrial projects from fundamental research studies on stem cells to artificial organ designing and development.
General Director
Sara Shamdani, ENG-Ph.D. has performed her master and doctorate thesis research at CNRS (French National Center for Scientific research) located at University of Paris Est (Créteil, France). She is specialist of Cell Therapy and Tissue Engineering and Extracellular Matrix Products. She has graduated from engineering school with a master in Environmental Engineering (water based disorders) and continued with another master in biotherapy of tissue, cells and genetics and PhD degree in Cellular and molecular biology. She has plenty of experience working in international private and public academic and research centers.
Chief Scientific Officer (CSO)
Georges Uzan, Ph.D. is Research Director at CNRS (French National Center for Scientific research). He is head of an INSERM (National Institute for Medical Research) unit located at Paul Brousse Hospital (Villejuif-France). His research interest is in the field of stem cells for different applications such as regenerative medicine, cardiovascular disorders and cancer. He is a well-known specialist of rare cells isolation and purification, characterization and culture. He has developed many research and industrial projects including many enterprises and biotech companies.
Marketing Officer
Jean-Pierre Mouscadet, HEC, Harvard PMD, General chemistry and biotechnology certificates, (Paris-Jussieu university and Arts et Métiers) has a long experience in sales people and distribution network management and has created companies devoted to distribution and productions of raw material for biotech research mainly in the cell culture domain.